INTRODUCTION
Infertility is a common aspect in about 15% of couples globally. Young couples under 35 years of age have the possibility of conceiving between 20 and 25% per month with a cumulative one-year rate of close to 90%. Those with sexual relations on demand and without contraceptive protection and who have not managed to conceive have a diagnosis of marital infertility and if this same couple (especially the woman) is over 37 years old, the diagnosis can be made in advance.
Currently, it is striking that a large number of people delay their time to IVF Center in Lahore due to socio-cultural factors that prefer personal and professional development over having children.
This phenomenon that began in developed countries is currently becoming very common in developing countries as well.
The rates of assisted fertilizations have increased significantly in recent decades, due to the exposed phenomenon; and the chances of finding a pregnancy have also become more feasible as scientific research on the matter has developed.
EVALUATION PRIOR TO IVF
Prior to carrying out IVF , couples have to go through a series of complementary examinations, which will allow evaluating different levels in the fertility process, some of them are: semen studies, evaluation of the female reproductive tract through hysterosalpingography, Hyster sonography, transvaginal ultrasound and tests to determine ovarian reserve such as. The latter due to the great variation between age and a woman’s ovarian reserve.
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Recent studies have shown that a low ovarian reserve is not only associated with a poor ovulatory response despite the use of exogenous gonadotropins but also with a lower recovery of oocytes, low oocyte quality and consequently a reduced embryonic quality; and globally a lower than expected pregnancy rate. Many women with unexplained infertility have an associated low ovarian response.
EVALUATION PRIOR TO IVF
Prior to carrying out IVF , couples have to go through a series of complementary examinations, which will allow evaluating different levels in the fertility process, some of them are: semen studies, evaluation of the female reproductive tract through hysterosalpingography, Hyster sonography, transvaginal ultrasound and tests to determine ovarian reserve such as. The latter due to the great variation between age and a woman’s ovarian reserve.
Recent studies have shown that a low ovarian reserve is not only associated with a poor ovulatory response despite the use of exogenous gonadotropins but also with a lower recovery of oocytes, low oocyte quality and consequently a reduced embryonic quality; and globally a lower than expected pregnancy rate. Many women with unexplained infertility have an associated low ovarian response.
RISKS OF IVF
As IVF techniques have become popular, the risks have increased; however, techniques and procedures are currently being studied and applied to reduce these effects.
Hyperstimulation syndrome, multiple pregnancies, congenital defects and others have been described with considerable emphasis in the 90’s.
Ovarian hyperstimulation syndrome
It is a short-term complication that can begin during gonadotropin stimulation or during the initial stage of pregnancy. It occurs 5% of the time and consists of: abdominal pain, hemodynamic alterations, ascites and ovarian congestion.
Multiple pregnancies
Although several couples from the Reproductive Medicine consultation report that they prefer to have twins to go through the experience of pregnancy in one go, it is true that a multiple gestation entails not only maternal but also fetal morbidity, the outcome of which can be catastrophic in the near future. 20% of the time.
Embryo transfer of more than 1 embryo significantly increases the rate of multiple pregnancies and best ivf in lahore is responsible for this occurring.
PREIMPLANTATION GENETIC DIAGNOSIS
Compared to sperm, eggs have a very prolonged meiosis, entering pro-phase I of the first meiotic division only in fetal life and remaining in this phase until the time of ovulation. As women age, there is a reduction in egg quality that leads to abnormalities in the chromosome spindle, which leads to aneuploidies.
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CONCLUSIONS
The comprehensive evaluation of the infertile couple is the first important step when defining the couple’s degree of infertility, providing specific treatment and offering them some of the available assisted reproduction techniques. The strategies to provide greater benefits and reduce the risk rate vary according to the training schools for subspecialists in Reproductive Medicine and Reproductive Biology, however they all aim to improve their pregnancy rates and, above all, provide an acceptable level of safety to patients. . It is essential that every fertility center report and periodically and publicly update their results for their own benefit and that of their patients.
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